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PHARMACOGNOSY: Effects of Cynodon dactylon on stress-induced infertility in male rats
VR Chidrawar, HR Chitme, KN Patel, NJ Patel, VR Racharla, NC Dhoraji, KR Vadalia
Journal of Young Pharmacists, Year 2011, Volume 3, Issue 1 [p. 26-35]
DOI: 10.4103/0975-1483.76416
Cynodon dactylon (Family: Poaceae) is known to be a tackler in Indian mythology and is offered to Lord Ganesha. It is found everywhere, even on waste land, road side, dry places, and spreads vigorously on cultivated ground. This study was carried out with an objective to test if the constituents of this plant are useful in coping stress-induced sexual In this study, we considered immobilization stress to induce male infertility and the effect of C. dactylon in restoration of the dysfunction was evaluated by considering sexual behavioral observations, sexual performance, fructose content of the seminal vesicles, epididymal sperm concentration and histopathological examinations as parameters. Treatment of rats under stress with methanolic extract of C. dactylon has shown a promising effect in overcoming stress-induced sexual dysfunction, sexual performance, fructose content, sperm concentration and its effect on accessory sexual organs and body weight. We conclude that active constituents of C. dactylon present in methanolic extract have a potent aphrodisiac and male fertility activity.
ORIGINAL ARTICLE: Quality Analysis of Manjishta (Rubia cordifolia L.) with respect to pharmacognostical and ...
Vivek Palengara, CM Harinarayanan, Pratibha P Nair
Pharmacognosy Magazine, Year 2021, Volume 17, Issue 5 [p. 45-53]
DOI: 10.4103/pm.pm_394_20
Background: The genuineness of Ayurvedic herbs causally determines the effectiveness of Ayurvedic treatment protocols. Research and subsequent evidence-based medicinal practices fundamentally dependant on appropriate identification and standardization of specific herbs are used for health-care purposes. Definite deficits that prevail in this regard in the form of adulteration, substitution, and compromised quality standards are the reasons why many scientific communities and health-related organizations question Ayurvedic sciences. This study aims at raising the very timely subject matter of genuine drug collection based on a model of Pharmacognostical and high-performance thin-layer chromatography (HPTLC) profiling of an Indian medicinal herb "Manjishta"' (Rubia cordifolia L.), a profoundly marketed Ayurvedic drug. Objectives: To compare the six market samples of Manjishta (Pharmacognostical and with HPTLC profiling) with the genuine root and stolon. Materials and Methods: The market samples of Manjishta from 6 districts of Kerala were collected, and these samples were compared with the genuine root and stolon (morphology, histology, and with HPTLC profiles). Results: Morphological and anatomical evaluation of the market samples was similar with that of the original stolon of Rubia cordifolia. HPTLC profiling yielded entirely different peaks in specific samples when compared with that of the genuine stolon. Conclusion: The collected market samples of Manjishta from different districts of Kerala were almost similar to the stolon of Rubia cordifolia L. A clear standard operative procedure should be prepared for medicinal plant part collection with respect to source plant maturity for Manjishta or as a matter of fact any other herb and thus the HPTLC profiles should be redefined.
LETTER TO THE EDITOR: Public hearing on the first naturopathy curriculum in Thailand
Viroj Wiwanitkit, Wasana Kaewla
Education for Health, Year 2015, Volume 28, Issue 3 [p. 213-214]
DOI: 10.4103/1357-6283.178601 PMID: 26996648
ORIGINAL ARTICLE: Access to healthcare among the Empowered Action Group (EAG) states of India: Current status and i...
Virendra Kumar, Pushpendra Singh
The National Medical Journal of India, Year 2016, Volume 29, Issue 5 [p. 267-273]
 PMID: 28098080
Background. Access to healthcare is crucial for meeting the health needs of Indians. We explored factors impeding access to public sources of healthcare among the Empowered Action Group (EAG) states of India. We also examined the extent to which Indians depend on public and private sources of healthcare in the EAG states. Methods. Our study is based on the unit-level records of 9988 ailing persons, who were surveyed among the EAG states in the 71st round of the National Sample Survey (NSS), conducted during January-June 2014 on the theme 'Social consumption: Health'. To analyse the socioeconomic factors, we did logistic regression using STATA version 12.0. Results. Despite a vast public health infrastructure in the EAG states, around three-fourths of inpatients are dependent on private sources of healthcare in both rural (70%) and urban (78%) areas. Poor quality and long waiting time in accessing healthcare from public health facilities remain big concerns for inpatients of the EAG states. Conclusion. To make public health services more accessible, there is a need to improve the quality of services, enlarge infrastructure to reduce waiting time, and enhance the physical reach to inpatients in the EAG states of India. Public health services will then be able to compete with those in the private sector.
ORIGINAL RESEARCH: Compare and evaluate the antibacterial efficacy of sodium hypochlorite and Calendula officinal...
Viraj S Yalgi, Kishor G Bhat
Journal of International Oral Health, Year 2020, Volume 12, Issue 1 [p. 74-79]
DOI: 10.4103/jioh.jioh_164_19
Aim: Elimination of microorganisms should be of priority in the treatment of any endodontic pathogenic process. The prevalence of microorganisms within the root canal will not cause treatment failures but the absence of microorganisms will certainly lead to success. Materials and Methods: In vivo study was conducted to compare the antibacterial effectiveness of sodium hypochlorite and Calendula officinalis against Streptococcus mutans as root canal irrigants. A total of 40 subjects (older than 18 years of age) were selected with single-rooted teeth, necrotic pulp, and chronic apical periodontitis. Access preparation was carried out, canal was negotiated and sample was taken with paper points before biomechanical preparation. After cleaning and shaping with ProTaper files, irrigation was carried out with sodium hypochlorite and C. officinalis, and was then neutralized with saline and then second sample was taken. Both samples were sent for culturing in pre-reduced medium. Mitis salivarius agar was used for S. mutans, and then calculation of the number of colony forming units per milliliter reduced transport fluid was carried out. Results: The results of the study showed good antibacterial potential for both the medicaments used. Conclusion: Sodium hypochlorite remains the gold standard for bacterial elimination in root canal therapy; however, C. officinalis also has shown promising results and may require further investigation.
ORIGINAL ARTICLE: A qualitative study on working experience of rural doctors in malappuram district of Kerala, India
Vinod Vallikunnu, S Ganesh Kumar, Sonali Sarkar, Sitanshu Sekhar Kar, KT Harichandrakumar
Journal of Family Medicine and Primary Care, Year 2014, Volume 3, Issue 2 [p. 141-145]
DOI: 10.4103/2249-4863.137643 PMID: 25161972
Background: Improving the working conditions of rural doctors is an important issue to increase the quality of health services to target groups. Objectives: To assess the working experience of rural doctors at primary health care level. Materials and Methods: This qualitative study was conducted among 30 medical officers from 21 primary health centers in Malappuram district of Kerala, India. In-depth interview was conducted, and content analysis was performed with the identification of themes based on the responses obtained. Results: There were 19 males and 11 females belonged to 25 to 55 years age group. About 70% (21) of them were graduates with MBBS qualification, and the rest were postgraduates. About 2/3 rd of them (20) had experience of less than 5 years. They expressed difficulty in managing the work in stipulated time period. However, this had never affected their OP management in anyway. They told that higher authorities were supportive, but they faced some opposition from the public in implementation of national program. Few opined that the training received was grossly insufficient in running the administrative affairs of the health center. Most of them satisfied with physical infrastructure, but manpower including medical officers and supporting staff were not sufficient. Some opined that the age of retirement is too early and should be increased. They participated in Continuing Medical Education, but expressed that it's content should suit to primary health care level. Conclusion: This study highlighted their concern to patient care and time, field work, administrative work, infrastructure, professional development, and future prospects. Further large scale evaluation studies will explore the situational analysis of it.
ORIGINAL ARTICLE: Prevalence of hypertension and diabetes morbidity among adults in a few urban slums of Bangalore ...
Vinod K Ramani, KP Suresh
Journal of Family Medicine and Primary Care, Year 2020, Volume 9, Issue 7 [p. 3264-3271]
DOI: 10.4103/jfmpc.jfmpc_234_20
Introduction: In World Health Organization's(WHO) South-East Asia region(SEAR), India accounts for >2/3rd of total deaths due to non-communicable diseases(NCD). Annually, NCDs account for ~60% of all deaths in India. Apart from the known risk factors, an individual's physical environment, behavioral and biological susceptibility are known to associated with NCDs. Social factors tend to create barriers for accessing healthcare among the poor people. Objectives: i)To screen and diagnose hypertension and diabetes among individuals aged >30 years, and its associated risk factors such as obesity and tobacco consumption. ii) To deliberate on the social determinants influencing this survey, and suggest suitable recommendations for the National Programme for prevention and control of Cancer, Diabetes, Cardiovascular disease and Stroke (NPCDCS). Methods: As a component of NPCDCS, the present survey was conducted in a few urban slums of Bangalore city during 2010. The collaborators for the conduct of this survey include the Ministry of health and family welfare, Director of health and family welfare services and Medical colleges in Bangalore city. Results: In our study, we found a prevalence proportion of 21.5% for hypertension, 13.8% for diabetes and 30.4% were co-morbid with both the diseases. Consumption of tobacco(any form) was present in 5.1% of the study subjects, overweight among 32.4% and obesity among 20.0%. The study population comprises 18.96% of the source, and the main reason for inadequate utilization was lack of Programmatic awareness. Conclusion: NPCDCS program needs to conceptualize the relevant social factors which determine access to screening and diagnostic healthcare services, including behavior change initiatives. For Program effectiveness, changes at the level of healthcare system need to adopted.
OPINION: Market forces in urological practice
Vilvapathy Senguttuvan Karthikeyan
Indian Journal of Urology, Year 2017, Volume 33, Issue 4 [p. 264-266]
DOI: 10.4103/iju.IJU_411_16 PMID: 29021648
ORIGINAL ARTICLE: A multipronged strategy operationalized to combat the COVID-19 pandemic in India
Vikas Bhatia, Neeraj Agarwal, Bijit Biswas
Biomedical and Biotechnology Research Journal (BBRJ), Year 2020, Volume 4, Issue 5 [p. 83-92]
DOI: 10.4103/bbrj.bbrj_138_20
Background: COVID-19 is an ongoing largest public health emergency of the 21st century. India is effectively controlling the pandemic by taking bold and stringent steps right from the beginning of the pandemic. This article aimed to formulate a multipronged strategy to combat the COVID-19 pandemic in India. Method: We have gone through websites of World Health Organization, Centers for Disease Control and Prevention, Indian Council of Medical Research, and Ministry of Health and Family Welfare of Government of India to avail updated information on COVID-19. Result: We found that there may be three pillars of this COVID-19 pandemic management, namely public health measures, diagnostic and testing, and hospital and health care. These pillars should be aimed to achieve three primary goals, namely containment, capacity building, and recovery. For India, gradual relaxation in lockdown with social distancing and personal and environmental hygiene measures must be the more suitable exit plan.
CASE REPORT: Nonspecific mesenteric lymphadenopathy in children and its management through Ayurveda: Two case ...
Vidya Bhushan Pandey
Journal of Ayurveda Case Reports, Year 2020, Volume 3, Issue 3 [p. 113-117]
DOI: 10.4103/JACR.JACR_34_20
Nonspecific mesenteric lymphadenopathy is one among the leading causes of cumbersome abdominal colic in children. The severity of the pain is variable and may cause emergency hospitalization in most of the cases. In Ayurveda, these complaints simulate with characteristics of Gulma (~abdominal mass or lump) where vitiated Vata dosha is responsible for clinical picture. Two cases of similar presentation of abdominal pain due to mesenteric lymphadenopathy are presented here. Ayurveda drugs such as Lavana bhaskara churna, Trikatu, Kanchanara guggulu, and Kumaryasava B have a textual indication for Gulma and administered along with Jahar mohra pishti, Panchamrita parpati, and Vidanga lauha. These were well tolerated by both the children. Treatment continued for 180 days. The pain was assessed with Wong-Baker Face scale (WBF scale) and Face, Leg, Activity, Cry, and Consolability scale (FLACC scale) according to the age group. After treatment, WBF scale showed a 2/10 score which was 8/10 before treatment and the FLACC scale showed a 0/10 score after treatment which was 10/10 before treatment. Relief in clinical symptoms was found, and the ultrasonography reports had shown improvement in the underlying pathology.
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