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SPECIAL ARTRICLE: Non-pathology: the bedrock of pathology.
ML Kothari, LA Mehta, VM Kothari
Journal of Postgraduate Medicine, Year 2000, Volume 46, Issue 2 [p. 134-43]
 PMID: 0011013487
Pathology, also called morbid anatomy, is macroscopically, microscopically, and molecularly so manifest an array of phenomena that it has compelled medical men to closely link it up with disease, dis-ease, and death. But there is more than meets the eye of the morbid anatomists, microscopists, and the molecular biologists. The obvious science of pathology is governed by numerous abstract, subtle, non-pathological factors. A pathological phenomenon is subservient to cosmic noumenon. Such a sea-change allows a newer perspective that cures modern medicine of many of its dogmas and provides epistemologically valid directions to research methodologies on the one hand and clinical practices on the other.
Gender and epilepsy : a Clinician's experience.
D Nag
Neurology India, Year 2000, Volume 48, Issue 2 [p. 99-104]
 PMID: 10878770
Women in India are greatly discriminated against if they happen to have epilepsy. Engagements are often cancelled. The parents of epileptic girls have to give heavy dowry at the time of marriage, even if the boy is handicapped. As a result, many girls do not disclose their problem before marriage. They take the medicine secretly. Epilepsy may sometimes produce problems during pregnancy and delivery, otherwise epileptic women on anti epileptic drugs, can lead a normal married, professional and social life. The stigma of epilepsy should be done away with, as we enter the 21st century.
EDITORIAL: Alternative medicine: Which way forward?
Kasim M Al-Dawood
Journal of Family and Community Medicine, Year 2000, Volume 7, Issue 2 [p. 13-15]
 PMID: 23008617
ORIGINAL ARTICLE: The pattern of alternative medicine use among patients attending health centres in a military com...
Eiad A Al-Faris
Journal of Family and Community Medicine, Year 2000, Volume 7, Issue 2 [p. 17-25]
 PMID: 23008618
Background: Alternative Medicine (AM) is gaining popularity worldwide. Objectives: This study was conducted to determine the prevalence and pattern of AM use in a military sector of the Saudi community. Methods: Three hundred and ten adult patients, visiting their family physicians over 6 weeks from the 1 st of June 1998, were selected by systematic random sampling. They were asked to report worrying health problems and their use of modern medicine (MM) and AM. Results: Forty-six percent of the patients had used AM before and about 19% had used it in the past 12 months. Alternative medicine practitioners were visited by 16.5% of the study population. Herbal medicine users represented 8.7% of the study population, honey (4.5%), the black grain Nigella sative (3%) and cautery was used by one person only. Women, housewives and the illiterate were more likely to use AM. About 86% of all the study population preferred MM. The main source of information about AM was relatives (77%). A large proportion of patients who reported depression used AM (53%) or visited AM practitioners (33%). The average cost per visit to an AM pratitioner (166 Saudi Riyals) was higher than that in the USA ($27.60=100 Saudi Riyals). Conclusion: There is a need to educate the public through the media and health professionals on the appropriate use of AM; housewives and the illiterate should be targeted. A community-based household survey using interviewers not associated with the health system such as teachers (to avoid bias) is needed.
ORIGINAL ARTICLE: A prospective randomized trial of open surgery versus endourological stone removal in patients of...
Anant Kumar, Balbir S Verma, Sanjay Gogoi, Rakesh Kapoor, Aneesh Srivastava, Anil Mandhani
Indian Journal of Urology, Year 2001, Volume 18, Issue 1 [p. 14-19]
Introduction: Renal stones with chronic renal failure (CRF) is a complex problem due to various inherent problems associated with CRP. Treating these stones is a challenge and therapy has to be tailored accordingly. Although there are many studies in the literature regarding the optimum management of staghorn stones with Percutaneous Nephrolithotomy (PCNL) alone or in combination with Extracorporeal Shock Wave Lithotripsy (ESWL); but the issue of staghorn stones with associated CRF has not been addressed adequately till date. Current study compares the role of open surgery vs PCNL in staghorn renal stones with CRF. Material and Methods: 26 patients with staghorn renal calculi and CRF were randomized to open (group I) and PCNL (group II) groups. The pre and postoperative hemoglobin (HB), hematocrit (HCT), serum creatinine and urine culture, size of stones, intraoperative blood loss, number of transfusions, surgical complications and duration of procedure was documented. Hemodialysis was done as and when necessary. The residual stone in both groups were treated with ESWL. Hospital stay and overall cost of treatment were analyzed. Results: A total of 10 patients were randomized to group I and 16 patients to group II (18 males and females). The two groups were comparable in terms of age (43.1 ± 13.9 vs 53.0 ± 15.5 yrs), preoperative serum creatinine (380.1 ± 247.5 vs 327.1 ± 88.4 pmol/L), Hb (88.0 ± 24.0 vs 95.0 ± 24.0 gm/L) and HCT (28.9 ± 7.9% vs 30.4 ± 7.3%). Stone size was 1713 ± 1470.2 and 1675 ± 2737.5 mm2 in group I and group 11 respectively. Preoperative culture was positive in 70% of open and 30% of PCNL group. The operating time (1160 ± 44.0 vs 152.5 ± 53 mins), and complication rate (10%in each) were similar in group 1 and group II respectively. Intraoperative blood loss was more in group II but it did not reach statistical significance. 1 patient in group I and 4 in group II required blood transfusion. The average number of sittings required in PCNL was 1.7 ± 0.67 with a puncture rate of 1.9 ± 0.73 per patient. Postoperative Hb, HCT, serum creatinine, bleeding, collections and fever were comparable in the two groups. Overall stone clearance (after adjuvant ESWL) was better in open (80%) as compared to PCNL (62.5%) group. The overall cost of treatment was significantly lower in open (Rs. 8333.3 ± 2851.3) as compared to PCNL (Rs. 16940 ± 4171.9). Hospital stay in the two groups was comparable (12.6 ± 6.1 and 12.9 ± 4.1 days in open and PCNL respectively). Conclusion: In view of the better clearance rate and lesser cost of treatment, open surgery still has a place in the management of staghorn stones with chronic renal failure even in a tertiary urological center. However postoperative pain and a larger scar cannot be ignored.
ARTICLE: Physico-chemical profile of some colouring plants used in homoeopathy
P Subramaniam, Sunilkumar
Ancient Science of Life, Year 2001, Volume 21, Issue 2 [p. 111-119]
The objective of this paper deal with the physico chemical aspects of certain colouring plants namely. Bixa orellana  Linn. (Leaves) and Lawsonia inermis  Linn (Leaves). The determined data under the physico chemical, chromatographic and spectrophotometric studies can be taken as a pharmacopoeial standards.
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EDUCATION: The relevance of spirituality in medical profession
Santosh Kumar
Indian Journal of Urology, Year 2002, Volume 18, Issue 2 [p. 207-212]
Patients expect holistic care from the medical profes­sion. In holistic care, the whole person comprising bodv, mind and spirit is given attention and six dimensions of health (physical, mental, emotional, spiritual, social and environmental) are recognised as being equally impor­tant. Patients' needs and expectations have forced the medical profession to recognise spiritual and religious factors in medical care. This article describes in detail the relevance of spirituality and religion in medical pr o­fession and suggests guidelines, for doctors for handling the spiritual and religious beliefs of patients.
SPECIAL ARTICLE: Medical ethics in the Neurosciences
SK Pandya
Neurology India, Year 2003, Volume 51, Issue 3 [p. 317-322]
 PMID: 14652429
Doctors in India are heirs to a long tradition of ethics from their own forebears and from those from the West. This paper discusses ethical aspects of topics of relevance to neurological scientists such as brain death, neural transplant and whole brain transplant. Many other topics such as ethics in research, patients with AIDS, patients in a persistent vegetative state and euthanasia deserve similar consideration and debate.
ORIGINAL ARTICLE: Epidemiological and Microbiological Diagnosis of Suppurative Keratitis in Gangetic West Bengal, E...
Samar K Basak, Sukumar Basak, Ayan Mohanta, Arup Bhowmick
Indian Journal of Ophthalmology, Year 2005, Volume 53, Issue 1 [p. 17-22]
DOI: 10.4103/0301-4738.15280 PMID: 15829742
PURPOSE: To determine the epidemiologcial pattern and risk factors involved in suppurative corneal ulceration in Gangetic West Bengal, eastern India, and to identify the specific microbial agents responsible for corneal infections. METHODS: All patients with suspected microbial keratitis presenting to the corneal clinic at Disha Eye Hospital, Barrackpore, West Bengal, India, from January 2001 to December 2003 were evaluated. Sociodemographic data and information pertaining to the risk factors were recorded. After diagnosing infective corneal ulcer clinically, corneal scraping and cultures were performed. RESULTS: Over a three-year period, 1198 patients with suppurative keratitis were evaluated. Ocular trauma was the most common predisposing factor in 994 (82.9%) patients (P< 0.0001), followed by use of topical corticosteroids in 231 (19.28%) patients. Cultures were positive in 811 (67.7%) patients. Among these culture positive cases, 509 (62.7%) patients had pure fungal infections (P< 0.001), 184 (22.7%) patients had pure bacterial infections and 114 (14.1%) had mixed fungal with bacterial infections. Acanthamoeba was detected in 4 (0.49%) patients. The most common fungal pathogen was Aspergillus spp representing 373 (59.8%) of all positive fungal cultures (P< 0.0001), followed by Fusarium spp in 132 (21.2%) instances. Most common bacterial isolate was Staphylococcus aureus, representing 127 (42.6%) of all the bacterial culture (P< 0.0001) followed by Pseudomonas spp 63 (21.1%). CONCLUSION: Suppurative keratitis in Gangetic West Bengal, most often occurs after a superficial corneal trauma with vegetative or organic materials. Fungal ulcers are more common than bacterial ulcers. Aspergillus spp and Staphylococcus aureus were the most common fungus and bacteria respectively. These ′regional′ findings have important public health implications for the treatment and prevention of suppurative corneal ulceration in this region of India.
RESEARCH LETTER: In vitro antioxidant properties of Solanum pseudocapsicum leaf extracts
S Badami, Om Prakash, SH Dongre, B Suresh
Indian Journal of Pharmacology, Year 2005, Volume 37, Issue 4 [p. 251-252]
DOI: 10.4103/0253-7613.16573
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