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Journal of Cancer Research and Therapeutics

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2009| September  | Volume 5 | Issue 9  

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EDITORIAL  
Tumors show enhanced dependency on glucose and glycolytic pathway p. 1
BS Dwarakanath, Nagraj G Huilgol
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REVIEW ARTICLES Top
Glucose deprivation-induced metabolic oxidative stress and cancer therapy p. 2
Andrean L Simons, David M Mattson, Ken Dornfeld, Douglas R Spitz
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Targeting energy metabolism in brain cancer through calorie restriction and the ketogenic diet p. 7
B Thomas N Seyfried, Michael Kiebish, Jeremy Marsh, Purna Mukherjee
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Enhancement of radiation and chemotherapeutic drug responses by 2-deoxy-D-glucose in animal tumors p. 16
Seema Gupta, Abdullah Farooque, JS Adhikari, Saurabh Singh, BS Dwarakanath
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Clinical studies for improving radiotherapy with 2-deoxy-D-glucose: Present status and future prospects p. 21
BS Dwarakanath, Dinesh Singh, Ajit K Banerji, Rajiv Sarin, NK Venkataramana, R Jalali, PN Vishwanath, BK Mohanti, RP Tripathi, VK Kalia, Viney Jain
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Cytotoxicity,radiosensitization, and chemosensitization of tumor cells by 2-deoxy-D-glucose In vitro p. 27
BS Dwarakanath
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Protection of normal cells and tissues during radio- and chemosensitization of tumors by 2-deoxy-D-glucose p. 32
Abdullah Farooque, Farhat Afrin, JS Adhikari, BS Dwarakanath
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Different ways to improve the clinical effectiveness of radioimmunotherapy in solid tumors p. 36
Jean-Francois Chatal, Francois Davodeau, Michel Cherel, Jacques Barbet
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ORIGINAL ARTICLES Top
Chemosensitizing and cytotoxic effects of 2-deoxy-D-glucose on breast cancer cells p. 41
Fanjie Zhang, Rebecca L Aft
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Differential responses of tumors and normal brain to the combined treatment of 2-DG and radiation in glioablastoma p. 44
Venkatesh K Prasanna, Neelam K Venkataramana, BS Dwarakanath, Vani Santhosh
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Modification of 2-deoxy-D-glucose on radiation-and chemotherapeutic drug-induced chromosomal aberrations p. 48
Venkatachalam Perumal, Paul FD Solomon, Vikram R Jayanth
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Modulatory action of 2-deoxy-D-glucose on mitomycin C-and 4-nitroquinoline-1-oxide-induced genotoxicity in Swiss albino mice In vivo p. 53
Rashmi Mohapatra, Arabandir Ramesh, Gopalsamy Jayaraman, Sathiyavedu Thyagarajan Santhiya, Puthiya Mundayat Gopinath
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Modulation of cellular radiation responses by 2-deoxy-D-glucose and other glycolytic inhibitors: Implications for cancer therapy p. 57
Vijay K Kalia, S Prabhakara, Vidya Narayanan
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Association between the unfolded protein response, induced by 2-deoxyglucose, and hypersensitivity to cisplatin: A mechanistic study employing molecular genomics p. 61
Shobhan Gaddameedhi, Satadal Chatterjee
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Short-term exposure of multicellular tumor spheroids of a human glioma cell line to the glycolytic inhibitor 2-deoxy-D-glucose is more toxic than continuous exposure p. 67
Divya Khaitan, Sudhir Chandna, S Bilikere Dwarakanath
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